Other ingredients
Alpha Lipoic Acid
Names you may see: alpha-lipoic acid ALA R-ALA R lipoic acid thioctic acid
The quick take
Alpha lipoic acid is a compound involved in cellular energy metabolism and antioxidant processes. It is different from the omega-3 fat alpha-linolenic acid, which is also abbreviated ALA.
A closer look
What forms will I see on a label?
Labels may list alpha lipoic acid, an R/S mixture or R-alpha lipoic acid (R-ALA). Compare the specified form and amount instead of assuming all preparations are equivalent.
Why people use it
People choose it for antioxidant and glucose-metabolism support. Sports brands also market it for nutrient-uptake goals, while clinical research has examined diabetic nerve symptoms.
These are common goals and marketing uses. The evidence section below explains what research supports.
What does the evidence tell us?
Studies of diabetic neuropathy have mixed results, although some suggest reduced pain. Evidence does not establish reliable blood-sugar control or muscle-building benefits, and it does not replace diabetes care.
What should I know before using it?
Digestive upset and headache can occur. Health Canada has linked alpha lipoic acid to rare insulin autoimmune syndrome causing low blood sugar. Stop use and seek medical advice for symptoms such as sweating, dizziness or confusion; review use with a clinician if taking diabetes medicine.
Sources & further reading
NIH NCCIH — alpha lipoic acid evidence ↗
Health Canada — alpha lipoic acid safety review ↗
Content reviewed: October 1, 2026
General educational information. Follow the product label and seek individual advice when needed.