Other ingredients
Betaine
Names you may see: trimethylglycine TMG betaine anhydrous betaine HCl
The quick take
Betaine, also called trimethylglycine, participates in methyl-group transfer and cellular fluid balance.
A closer look
What forms will I see on a label?
Sports products usually use betaine anhydrous. Betaine hydrochloride (HCl), used in digestive products, is a different formulation and should not be treated as a direct substitute.
Why people use it
Marketed for strength, power and training performance, usually as betaine anhydrous in sports formulas.
These are common goals and marketing uses. The evidence section below explains what research supports.
What does the evidence tell us?
Small exercise studies have produced mixed findings. A possible effect on strength or power should not be presented as a guaranteed training benefit.
What should I know before using it?
Follow the directions and cautions on the specific product. Ask a pharmacist about suitability if you take medication or have a medical condition.
Sources & further reading
NIH Office of Dietary Supplements ↗
Content reviewed: September 30, 2026
General educational information. Follow the product label and seek individual advice when needed.