Fats & oils
Phosphatidylserine
Names you may see: PS phosphatidyl serine soy phosphatidylserine sunflower phosphatidylserine
The quick take
Phosphatidylserine is a phospholipid, a type of fat that forms part of cell membranes, including those in the brain.
A closer look
What forms will I see on a label?
Supplements can use different source materials, including soy or sunflower. Compare the actual phosphatidylserine amount rather than the total lecithin or phospholipid-complex weight.
Why people use it
People choose it for memory, focus and stress-management goals. Some bodybuilders and athletes use it with the aim of moderating the cortisol response to training.
These are common goals and marketing uses. The evidence section below explains what research supports.
What does the evidence tell us?
Memory research is limited and includes subgroup findings in older adults with memory complaints. Small exercise studies have measured cortisol changes, but this does not establish better muscle growth, recovery or performance.
What should I know before using it?
Check source and allergen information, especially for soy-derived products. Discuss persistent memory changes with a clinician. Evidence is limited during pregnancy and breastfeeding and for long-term use.
Sources & further reading
Published phosphatidylserine memory trial ↗
Published phosphatidylserine exercise trial ↗
Content reviewed: October 1, 2026
General educational information. Follow the product label and seek individual advice when needed.