Amino acids & related
Creatine
Names you may see: creatine monohydrate micronized creatine HCl
The quick take
Creatine helps muscles replenish energy during short, intense efforts. Creatine monohydrate is the most widely studied supplemental form.
A closer look
What forms will I see on a label?
Monohydrate and creatine HCl are different forms. Micronized describes particle size; it does not mean a different creatine molecule.
Why people use it
Used to support strength, repeated high-intensity efforts and muscle gains alongside resistance training.
These are common goals and marketing uses. The evidence section below explains what research supports.
What does the evidence tell us?
Evidence supports repeated high-intensity exercise and improved training capacity. Results depend on the activity and training program; creatine is not a stimulant.
What should I know before using it?
An increase in body weight from water retention can occur. Follow the label and ask a clinician about suitability if you have kidney disease or another relevant medical condition.
Sources & further reading
NIH Office of Dietary Supplements ↗
Content reviewed: September 30, 2026
General educational information. Follow the product label and seek individual advice when needed.