Other ingredients
DMSO
Names you may see: dimethyl sulfoxide dimethylsulfoxide
The quick take
DMSO is a chemical solvent with specific medical uses. It is included here for reference, not as a routine oral supplement.
A closer look
What forms will I see on a label?
Topical and medical preparations are not interchangeable. DMSO is different from MSM, another sulfur-containing compound.
Why people use it
Some people seek it for topical joint or muscle comfort. These uses should be distinguished from supervised medical treatment.
These are common goals and marketing uses. The evidence section below explains what research supports.
What does the evidence tell us?
Research on topical DMSO for osteoarthritis is too limited for firm conclusions. Its medical use for bladder symptoms involves administration into the bladder by a healthcare professional.
What should I know before using it?
Do not ingest industrial or topical DMSO or use this guide as directions for self-treatment. Skin irritation, digestive effects and garlic-like odour can occur; industrial products may contain contaminants. Seek professional advice before use.
Sources & further reading
NCCIH — DMSO evidence and safety ↗
Content reviewed: September 30, 2026
General educational information. Follow the product label and seek individual advice when needed.