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Serrapeptase

Names you may see: serratiopeptidase serrapeptidase proteolytic enzyme

The quick take

Serrapeptase, also called serratiopeptidase, is a protein-breaking enzyme.

A closer look

What forms will I see on a label?

Labels may state enzyme activity units as well as milligrams. These measurements are not interchangeable.

Why people use it

It is marketed for swelling, tissue comfort and recovery; some products also make circulation claims.

These are common goals and marketing uses. The evidence section below explains what research supports.

What does the evidence tell us?

Clinical studies are generally small or methodologically limited. Evidence does not establish broad recovery benefits or the ability to clear arterial plaque, and long-term safety data are inadequate.

What should I know before using it?

Discuss use with a clinician, particularly before surgery or with medicines that affect bleeding. It is not a substitute for prescribed treatment or assessment of persistent pain or swelling.

Sources & further reading

Published serratiopeptidase evidence review ↗

Additional serratiopeptidase review ↗

Content reviewed: September 30, 2026

General educational information. Follow the product label and seek individual advice when needed.