Other ingredients
Synephrine
Names you may see: p-synephrine bitter orange citrus aurantium
The quick take
Synephrine is a compound associated with bitter orange and some stimulant-style weight-management formulas.
A closer look
What forms will I see on a label?
An amount of bitter-orange extract is not an equivalent amount of synephrine. Review the declared compound content and other stimulant ingredients.
Why people use it
Marketed in thermogenic products for increased calorie burning and weight management. It is associated with bitter-orange extracts.
These are common goals and marketing uses. The evidence section below explains what research supports.
What does the evidence tell us?
Evidence for meaningful weight loss is limited. Research involving caffeine or other ingredients cannot establish synephrine’s independent effect.
What should I know before using it?
Heart rate and blood-pressure concerns are particularly relevant with stimulant combinations. Discuss cardiovascular conditions and medicines with a professional.
Sources & further reading
NIH Office of Dietary Supplements ↗
Content reviewed: September 30, 2026
General educational information. Follow the product label and seek individual advice when needed.